منابع مشابه
Glucosamine Metabolism
Recent studies in this laboratory, concerned with hexosamine metabolism, required Gm-6-P,’ Galm-BP, and their respective N-acetyl derivatives. Several methods are available for the preparation of Cm-6-P, but there appears to be no previous report of Calm-6-P, although an acid-stable Galm-P has been isolated from cartilage (4). Earlier reports indicated that hexokinase and ATP would phosphorylat...
متن کاملGlucosamine metabolism. V. Enzymatic synthesis of glucosamine 6-phosphate.
Studies in viva on the biosynthesis of n-glucosamine, with the use of specifically labeled glucose in the rat (1,2) and in group A streptococci (3-5) showed that the glucose carbon chain was preserved during its conversion to the hexosamine. Leloir and Cardini (6, 7) noted that extracts obtained from Neurospora crassa converted glutamine and hexose phosphate to glutamic acid and a product tenta...
متن کاملMetabolism of D-Glucosamine and kketyl-D- glucosamine in the Intact Rat*
It has been demonstrated that n-glucosamine and N-acetyln-glucosamine are metabolized in animal tissues to n-fructose via phosphorylated intermediates (14). It has also been shown that n-glucose is converted to n-glucosamine and incorporated into glycoproteins and mucopolysaccharides (Pll), probably through formation of uridine diphosphate derivatives as intermediates (4). Little work has been ...
متن کاملMetabolism of D-glucosamine and N-acetyl-D-glucosamine in the intact rat.
It has been demonstrated that n-glucosamine and N-acetyln-glucosamine are metabolized in animal tissues to n-fructose via phosphorylated intermediates (14). It has also been shown that n-glucose is converted to n-glucosamine and incorporated into glycoproteins and mucopolysaccharides (Pll), probably through formation of uridine diphosphate derivatives as intermediates (4). Little work has been ...
متن کاملGlucosamine.
Glucosamine is one of the most popular dietary supplements sold in the United States. Most clinical trials have focused on its use in osteoarthritis of the knee. The reported adverse effects have been relatively well studied and are generally uncommon and minor. No significant supplement-drug interactions involving glucosamine have been reported. The National Institutes of Health-sponsored Gluc...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64810-0